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A premature ventricular contraction (PVC) is a common event where the heartbeat is initiated by Purkinje fibers in the ventricles rather than by the sinoatrial node. PVCs may cause no symptoms or may be perceived as a "skipped beat" or felt as palpitations in the chest. PVCs do not usually pose any danger. [1]
Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity. [1] This can cause heart failure, arrhythmia, myocarditis, and cardiomyopathy in patients. [2] Some effects are reversible, while in others, permanent damage requiring further treatment may arise.
This can actually trigger a heart attack in people with cardiac structural abnormalities i.e. coronary bridge, missing coronary, and atherosclerosis. If the heart rate drops too low for too long, catecholamines are released to counteract any lowering of blood pressure.
The compensatory constriction of the arteries and increased heart rate can cause blood pressure to overshoot normal values, triggering the opposite baroreflex. This time, the brain increases parasympathetic signalling and decreases sympathetic signalling, causing a decrease in heart rate (the turbulence slope part of HRT).
“Heart disease” can refer to several types of heart conditions, but the most common in the U.S. is coronary artery disease, which affects blood flow and can lead to a heart attack. The AHA ...
This can lead to cardiac hypertrophy, dilatation of the heart, and ultimately heart failure in some cases. [1] The right side of the heart is much smaller and weaker than the left side of the heart. It pumps de-oxygenated blood into the lungs. The left side of the heart is more muscular than the right side of the heart.
High-output heart failure can occur when there is increased cardiac demand that results in increased left ventricular diastolic pressure which can develop into pulmonary congestion (pulmonary edema). [46] Several terms are closely related to heart failure and may be the cause of heart failure, but should not be confused with it.
The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle, through damage or overloading. As such, it can be caused by a wide number of conditions, including myocardial infarction (in which the heart muscle is starved of oxygen and dies), hypertension (which increases the force of contraction needed to pump blood) and cardiac amyloidosis (in which misfolded ...
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