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  2. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    An additional 237 million men and 46 million women have alcohol use disorder as of 2016. [18] In 2017, substance use disorders from illicit substances directly resulted in 585,000 deaths. [17] Direct deaths from drug use, other than alcohol, have increased over 60 percent from 2000 to 2015. [19]

  3. Substance-related disorder - Wikipedia

    en.wikipedia.org/wiki/Substance-related_disorder

    Substance use, also known as drug use, is a patterned use of a substance (drug) in which the user consumes the substance in amounts or with methods which are harmful to themselves or others. The drugs used are often associated with levels of substance intoxication that alter judgment, perception, attention and physical control, not related with ...

  4. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    Of these, 27 million have high-risk drug use—otherwise known as recurrent drug use—causing harm to their health, causing psychological problems, and or causing social problems that put them at risk of those dangers. [2] [3] In 2015, substance use disorders resulted in 307,400 deaths, up from 165,000 deaths in 1990.

  5. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    Signs and symptoms of drug addiction can vary depending on the type of addiction. Symptoms may include: Continuation of drug use despite the knowledge of consequences [12] Disregarding financial status when it comes to drug purchases; Ensuring a stable supply of the drug; Needing more of the drug over time to achieve similar effects [12]

  6. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  7. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    Drug use, including alcohol and prescription drugs, can induce symptomatology which resembles mental illness. This can occur both in the intoxicated state and during the withdrawal state. In some cases these substance-induced psychiatric disorders can persist long after detoxification from amphetamine, cocaine, opioid, and alcohol use, causing ...

  8. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Addiction is a brain disorder characterized by compulsive drug use despite adverse consequences. [36] [57] [58] [59] Addiction involves the overstimulation of the brain's mesocorticolimbic reward circuit (reward system), essential for motivating behaviors linked to survival and reproductive fitness, like seeking food and sex. [60]

  9. Physical dependence - Wikipedia

    en.wikipedia.org/wiki/Physical_dependence

    Physical dependence is usually managed by a slow dose reduction over a period of weeks, months or sometimes longer depending on the drug, dose and the individual. [6] A physical dependence on alcohol is often managed with a cross tolerant drug, such as long acting benzodiazepines to manage the alcohol withdrawal symptoms.