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BER is initiated by DNA glycosylases, which recognize and remove specific damaged or inappropriate bases, forming AP sites. These are then cleaved by an AP endonuclease . The resulting single-strand break can then be processed by either short-patch (where a single nucleotide is replaced) or long-patch BER (where 2–10 new nucleotides are ...
Apurinic/apyrimidinic (AP) endonuclease is an enzyme that is involved in the DNA base excision repair pathway (BER). Its main role in the repair of damaged or mismatched nucleotides in DNA is to create a nick in the phosphodiester backbone of the AP site created when DNA glycosylase removes the damaged base.
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AP Lockheed disc brake caliper. Automotive Products, commonly abbreviated to AP, was an automotive industry components company set up in 1920 by Edward Boughton, Willie Emmott and Denis Brock, to import and sell American-made components to service the fleet of ex-military trucks left behind in Europe after World War I.
The fire burned 34 acres, but forward progress was stopped around 3:30 p.m., the San Bernardino County Fire Department said.. A man was taken into custody and charged with two felony charges ...
Keeping pace with the S&P 500 in 2024 has been a challenge, even for well-known growth stocks like Microsoft, which rallied big time in 2023. Only 144 S&P 500 components, or less than 29%, are ...
Pete Hegseth, President-elect Donald Trump's choice to be Defense secretary, appears before the Senate Armed Services Committee for his confirmation hearing, at the Capitol in Washington, Tuesday ...
AP [3] AP-AAA to AP-ZZZ, civil aircraft, from 1947 Panama: HP [1] HP-1000AAA to HP-9999ZZZ. The three letters (AAA–ZZZ) stand for the ICAO code of the airline, such as CMP for Copa Airlines and PST for Air Panama. Papua New Guinea: P2 [3] P2-AAA to P2-ZZZ Paraguay: ZP [3] ZP-AAA to ZP-ZZZ Peru: OB [1]