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Secondary tumors in the CNS, or metastatic tumors, occur when cancer cells spread to the brain or spinal cord from a primary tumor in another part of the body. These tumors are more common than primary CNS tumors in adults and often originate from cancers of the lung , breast , skin , kidney , or colon .
Radiation-induced lumbar plexopathy (RILP) or radiation-induced lumbosacral plexopathy (RILSP) is nerve damage in the pelvis and lower spine area caused by therapeutic radiation treatments. RILP is a rare side effect of external beam radiation therapy [ 1 ] [ 2 ] [ 3 ] and both interstitial and intracavity brachytherapy radiation implants.
The ESMO Clinical Practice Guidelines (CPG) are intended to provide oncology professionals with a set of recommendations for the best standards of cancer care, based on the findings of evidence-based medicine. Each Clinical Practice Guideline includes information on the incidence of the malignancy, diagnostic criteria, staging of disease and ...
Spinal cord compression is commonly found in patients with metastatic malignancy. [10] Back pain is a primary symptom of spinal cord compression in patients with known malignancy. [11] Back pain may prompt a bone scan to confirm or exclude spinal metastasis. Rapid identification and intervention of metastatic spinal cord compression is ...
Cancer should be suspected if there is previous history of cancer, unexplained weight loss, or low-back pain that does not decrease by lying down or is unremitting. [3] Spinal epidural abscess is more common among those with diabetes mellitus or immunocompromised , who use intravenous drugs , or had spinal surgery , injection or catheter ; it ...
Spread of cancer to the bone or spinal cord can lead to back pain. Bone is one of the most common sites of metastatic lesions. Patients typically have a history of malignancy. Common types of cancer that present with back pain include multiple myeloma, lymphoma, leukemia, spinal cord tumors, primary vertebral tumors and prostate cancer. [14]
The concept of a spine care clinician or practitioner was first presented by neurologist Scott Haldeman in an editorial in The Spine Journal in 2001. [5] The PSP role may include all clinical specialties that treat patients with spinal disease. This was emphasized at the American Back Society Annual Convention in San Francisco in November 2005. [6]
Clinical guidelines for prescribing opioids for chronic pain have been issued by the American Pain Society and the American Academy of Pain Medicine. Included in these guidelines is the importance of assessing the patient for the risk of substance abuse, misuse, or addiction.