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  2. Histidine decarboxylase - Wikipedia

    en.wikipedia.org/wiki/Histidine_decarboxylase

    In mammals, histamine is an important biogenic amine with regulatory roles in neurotransmission, gastric acid secretion and immune response. [1] [2] Histidine decarboxylase is the sole member of the histamine synthesis pathway, producing histamine in a one-step reaction. Histamine cannot be generated by any other known enzyme.

  3. H3 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H3_receptor_antagonist

    An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...

  4. Antihistamine - Wikipedia

    en.wikipedia.org/wiki/Antihistamine

    An H 3-antihistamine is a classification of drugs used to inhibit the action of histamine at the H 3 receptor. H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of histamine .

  5. 16 Ways to Get Rid of Hives, According to Doctors - AOL

    www.aol.com/16-ways-rid-hives-according...

    The histamine release causes allergy symptoms, such as hives. ... reducing itching and swelling by blocking the body’s histamine response,” Hwang explains. 3. Try an Over-the-Counter Steroid ...

  6. Histamine liberators - Wikipedia

    en.wikipedia.org/wiki/Histamine_liberators

    Histamine is an organic compound that primarily functions in service of the human body's immune responses as well as for the regulation of many physiological functions. [1] Since their discovery in 1910, [ 2 ] histamines have been known to trigger inflammatory responses such as itching as part of an immune response to foreign pathogens; for ...

  7. H1 antagonist - Wikipedia

    en.wikipedia.org/wiki/H1_antagonist

    H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.

  8. Mast cell stabilizer - Wikipedia

    en.wikipedia.org/wiki/Mast_cell_stabilizer

    They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected pharmacodynamic mechanism is the blocking of IgE-regulated calcium channels. Without intracellular calcium, the histamine vesicles cannot fuse to the cell membrane and degranulate. [1]

  9. Histamine H3 receptor - Wikipedia

    en.wikipedia.org/wiki/Histamine_H3_receptor

    Like all histamine receptors, the H 3 receptor is a G-protein coupled receptor. The H 3 receptor is coupled to the G i G-protein , so it leads to inhibition of the formation of cAMP . Also, the β and γ subunits interact with N-type voltage gated calcium channels , to reduce action potential mediated influx of calcium and hence reduce ...

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