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  2. Pathophysiology of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_HIV/AIDS

    HIV is commonly transmitted via unprotected sexual activity, blood transfusions, hypodermic needles, and from mother to child. Upon acquisition of the virus, the virus replicates inside and kills T helper cells , which are required for almost all adaptive immune responses .

  3. HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/HIV/AIDS

    HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90] Lentiviruses share many morphological and biological characteristics.

  4. HIV - Wikipedia

    en.wikipedia.org/wiki/HIV

    Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was initially discovered and termed both lymphadenopathy associated virus (LAV) and human T-lymphotropic virus 3 (HTLV-III). HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower ...

  5. Epidemiology of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Epidemiology_of_HIV/AIDS

    HIV testing is an essential gateway to HIV prevention, treatment, care and support services. [31] It is crucial to have HIV tests available for individuals worldwide since it can help individuals detect the status of their disease from an early onset, seek help, and prevent further spread through the practice of suggestive safety precautions.

  6. WHO Disease Staging System for HIV Infection and Disease in ...

    en.wikipedia.org/wiki/WHO_Disease_Staging_System...

    HIV encephalopathy; The presumptive criteria are designed for use where access to confirmatory diagnostic testing for HIV infection by means of virological testing (usually nucleic acid testing, NAT) or P24 antigen testing for infants and children aged under 18 months is not readily available.

  7. Immune reconstitution inflammatory syndrome - Wikipedia

    en.wikipedia.org/wiki/Immune_reconstitution...

    Immune reconstitution inflammatory syndrome (IRIS) is a condition seen in some cases of HIV/AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.

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  9. HIV and pregnancy - Wikipedia

    en.wikipedia.org/wiki/HIV_and_pregnancy

    The most updated HIV testing protocols recommend using the HIV-1 and HIV-2 antigen/antibody combination immunoassay as the initial screening test for an HIV infection. [22] This blood test assesses whether or not the mother has created antibodies , which are disease-fighting proteins of the immune system, against the HIV-1 and HIV-2 viruses.

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