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Central cyanosis occurs due to decrease in arterial oxygen saturation (SaO2), and begins to show once the concentration of deoxyhemoglobin in the blood reaches a concentration of ≥ 5.0 g/dL (≥ 3.1 mmol/L or oxygen saturation of ≤ 85%). [4] This indicates a cardiopulmonary condition. [1] Causes of central cyanosis are discussed below.
Acrocyanosis may be a sign of a more serious medical problem, such as connective tissue diseases and diseases associated with central cyanosis. Other causative conditions include infections, toxicities, antiphospholipid syndrome, cryoglobulinemia, neoplasms. In these cases, the observed cutaneous changes are known as "secondary acrocyanosis".
Blue baby syndrome can refer to conditions that cause cyanosis, or blueness of the skin, in babies as a result of low oxygen levels in the blood. This term has traditionally been applied to cyanosis as a result of:. [1] Cyanotic heart disease, which is a category of congenital heart defect that results in low levels of oxygen in the blood. [2]
Cyanosis, a bluish tinge of the extremities (peripheral cyanosis), or of tongue (central cyanosis) [4] Pursed-lip breathing [5] Accessory muscle use, including the scalene and intercostal muscles [5] Diaphragmatic breathing, paradoxical movement of the diaphragm outwards during inspiration; Intercostal indrawing
Hippocratic fingers: Hippocrates: pulmonary medicine: chronic hypoxia: clubbing of distal phalanges Hirschberg test: Julius Hirschberg: ophthalmology: strabismus: corneal reflection centred (-) or not centred (+) on pupil Hoffmann's sign: Johann Hoffmann: neurology: corticospinal tract lesions: tapping distal phalanx of 3rd or 4th finger ...
Nail clubbing, also known as digital clubbing or clubbing, is a deformity of the finger or toe nails associated with a number of diseases, anomalies and defects, some congenital, mostly of the heart and lungs. [2] [3] When it occurs together with joint effusions, joint pains, and abnormal skin and bone growth it is known as hypertrophic ...
ZCCHC18 ubiquitously expresses in ovary, brain (cerebellum), endometrium, lymph node, spleen and 22 other tissues in human and other species. [11] Based on RNA-Seq expression data from GTEx (53 tissues from 570 donors), highest median expression is in brain—cerebellum (4.74 RPKM) whereas the total median expression of 67.54 RPKM.
A cyanotic heart defect is any congenital heart defect (CHD) that occurs due to deoxygenated blood bypassing the lungs and entering the systemic circulation, or a mixture of oxygenated and unoxygenated blood entering the systemic circulation.