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Myofilaments are the three protein filaments of myofibrils in muscle cells. The main proteins involved are myosin , actin , and titin . Myosin and actin are the contractile proteins and titin is an elastic protein.
A myofibril (also known as a muscle fibril or sarcostyle) [1] is a basic rod-like organelle of a muscle cell. [2] Skeletal muscles are composed of long, tubular cells known as muscle fibers, and these cells contain many chains of myofibrils. [3] Each myofibril has a diameter of 1–2 micrometres. [3]
Cardiac muscle like the skeletal muscle is also striated and the cells contain myofibrils, myofilaments, and sarcomeres as the skeletal muscle cell. The cell membrane is anchored to the cell's cytoskeleton by anchor fibers that are approximately 10 nm wide. These are generally located at the Z lines so that they form grooves and transverse ...
Skeletal muscle cell types include: very large multinuclear muscle fiber cells; small endothelial cells that line the inside of capillary blood vessels; small fibro-adipogenic progenitor cells (FAPs) which are muscle-fiber-adjacent multipotent mesenchymal stem cells that under different conditions can differentiate into adipocytes, fibroblasts ...
For a muscle cell to contract, tropomyosin must be moved to uncover the binding sites on the actin. Calcium ions bind with troponin C molecules (which are dispersed throughout the tropomyosin protein) and alter the structure of the tropomyosin, forcing it to reveal the cross-bridge binding site on the actin.
During contraction of a cardiac muscle cell, the long protein myofilaments oriented along the length of the cell slide over each other in what is known as the sliding filament theory. There are two kinds of myofilaments, thick filaments composed of the protein myosin, and thin filaments composed of the proteins actin, troponin and tropomyosin ...
Myocytes are incredibly specialized cells with only a select number of different organelle types. A myocyte is composed of multiple myofibrils, which contain the “contractile units” of the muscle known as a sarcomere. [3] These sarcomeres are arranged in adjacent formations along the myofibrils.
A smooth-muscle cell is a spindle-shaped myocyte with a wide middle and tapering ends, and a single nucleus. Like striated muscle, smooth muscle can tense and relax. In the relaxed state, each cell is 30–200 micrometers in length, some thousands of times shorter than a skeletal muscle cell. [1]