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WAP four-disulfide core domain protein 2 - also known as Human Epididymis Protein 4 [5] (HE4) - is a protein that in humans is encoded by the WFDC2 gene. [ 6 ] [ 7 ] [ 8 ] HE4 is a tumor marker of ovarian cancer , with 80% sensitivity at a cut-off of 150 pmol/L. [ 9 ]
Although hematometra can often be diagnosed based purely on the patient's history of amenorrhea and cyclic abdominal pain, as well as a palpable pelvic mass on examination, the diagnosis can be confirmed by ultrasound, which will show blood pooled in the uterus and an enlargement of the uterine cavity.
Other types of cancer include cervical cancer; bleeding in that case can sometimes be triggered by postcoital bleeding. Cancers of the vagina or fallopian tubes are rare causes of hemorrhage. Uterine fibroids represent a common, benign condition that may lead to bleeding, specifically if the lesion affects the uterine cavity.
Uterine cancer is the fourth most common cancer in females in the UK (around 8,500 women were diagnosed with the disease in 2011), and it is the tenth most common cause of cancer death in females (around 2,000 women died in 2012).
But in the new study, which included data for about 1,500 Black patients, more than 11% of those with endometrial cancer (24 of 210 people) had endometrial thickness measurements that fell within ...
Initial evaluation during diagnosis aims at determining pregnancy status, menopausal status, and the source of bleeding. One definition for diagnosing the condition is bleeding lasting more than 7 days or the loss of more than 80 mL of blood heavy flow. [3] Treatment depends on the cause, severity, and interference with quality of life. [4]
In patients with suspected uterine cancer, the biopsy may discover the presence of cancer cells in the endometrium or cervix. In female infertility the assessment of the lining can determine, if properly timed, that the patient ovulated, however, the same information can be obtained by a blood test of the progesterone level.
The medical definition of hematocolpos is "an accumulation of blood within the vagina". It is often caused by the combination of menstruation with an imperforate hymen. [1] [2] It is sometimes seen in Robinow syndrome, uterus didelphys, or other vaginal anomalies. A related disorder is hematometra, where the uterus fills with menstrual blood. [3]