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Bioconcentration. In aquatic toxicology, bioconcentration is the accumulation of a water-borne chemical substance in an organism exposed to the water. [ 1][ 2] There are several ways in which to measure and assess bioaccumulation and bioconcentration. These include: octanol-water partition coefficients (K OW ), bioconcentration factors (BCF ...
The Biopharmaceutics Classification System (BCS) is a system to differentiate drugs on the basis of their solubility and permeability. [1] This system restricts the prediction using the parameters solubility and intestinal permeability. The solubility classification is based on a United States Pharmacopoeia (USP) aperture.
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Survival function. The survival function is a function that gives the probability that a patient, device, or other object of interest will survive past a certain time. [ 1] The survival function is also known as the survivor function[ 2] or reliability function. [ 3] The term reliability function is common in engineering while the term survival ...
The Variant Call Format or VCF is a standard text file format used in bioinformatics for storing gene sequence variations. The format was developed in 2010 for the 1000 Genomes Project and has since been used by other large-scale genotyping and DNA sequencing projects. [ 1][ 2] VCF is a common output format for variant calling programs due to ...
Calculation. A measure of the state of health of a person or group in which the benefits, in terms of length of life, are adjusted to reflect the quality of life. One quality-adjusted life year (QALY) is equal to 1 year of life in perfect health. [ 4] It combines two different benefits of treatment—length of life and quality of life—into a ...
Bivariate data. In statistics, bivariate data is data on each of two variables, where each value of one of the variables is paired with a value of the other variable. [1] It is a specific but very common case of multivariate data. The association can be studied via a tabular or graphical display, or via sample statistics which might be used for ...