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Iron Compound Iron Dextran Iron Dextan Sodium Ferric Gluconate Iron Sucrose Ferumoxytol Iron Isomaltoside Iron Carboxymaltose Molecular weight 265 000 high molecular weight iron dextran 165 000 low molecular weight iron dextran 289 000 - 444 000 34 000 - 60 000 750 000 150 000 150 000 Maximum approved dosage (mg) 100 100 125 200 510 20 mg per kg
Iron is mostly conserved and recycled in the body with minimal loss. [18] A very limited loss is estimated to be approximately 1 mg/day, [19] mainly by sweating and epithelial cell exfoliation on the skin, genitourinary tract, and gastrointestinal tract. For women, menstrual bleeding is another route for iron loss. [18]
Injectable forms include iron dextran and iron sucrose. [13] They work by providing the iron needed for making red blood cells. [14] Iron pills have been used medically since at least 1681, with an easy-to-use formulation being created in 1832 using Chicken Liver extracts and majority from plants. [15]
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Iron sucrose has ~20 mg of iron per mL of solution. A typical adult patient can safely receive 600 mg of iron sucrose per week, administered in separate doses of 200–300 mg. Most patients experience an increase in their hemoglobin levels of at least 20 g/L. [ 3 ] Administration usually takes from fifteen to thirty minutes [ 3 ] and is done by ...
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