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"Surgical removal of the vitreous gel by a vitreoretinal surgeon can sometimes be performed to achieve symptomatic relief," says Dr. Sastry. 4. Consider other options for the most severe cases
Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor. [1] It is used to treat various eye diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and infections inside the eye such as endophthalmitis. [1]
Rhegmatogenous retinal detachment is most commonly caused by posterior vitreous detachment, a condition where the gel inside the eye breaks down and pulls on the retina. [4] [7] Risk factors include older age, nearsightedness , eye injury, cataract surgery, and inflammation. [7] [8]
The vitreous fluid is not present at birth (the eye being filled with only the gel-like vitreous body), but found after age 4-5, and increases in size thereafter. [1] Produced by cells in the non-pigmented portion of the ciliary body, the vitreous humour is derived from embryonic mesenchyme cells, which degenerate after birth. [1]
Intravitreal administration is a route of administration of a drug, or other substance, in which the substance is delivered into the vitreous humor of the eye. "Intravitreal" literally means "inside an eye". Intravitreal injections were first introduced in 1911 when Ohm gave an injection of air into the vitreous humor to repair a detached retina.
Vitreomacular adhesion (VMA) is a human medical condition where the vitreous gel (or simply vitreous, AKA vitreous humour) of the human eye adheres to the retina in an abnormally strong manner. As the eye ages, it is common for the vitreous to separate from the retina.
The eye's immune-privileged status reduces the likelihood of immune responses to the viral vector, increasing the therapy's safety profile. Emerging clinical trials are exploring this modality's potential, with promising results indicating sustained benefits over months or years after a single treatment. Despite its potential, challenges remain.
The vitreous humour, or vitreous body, is a jelly-like, transparent substance that fills the majority of the eye. It lies within the vitreous chamber behind the lens, and is one of the four optical components of the eye. [8] Thus, floaters follow the rapid motions of the eye, while drifting slowly within the pocket of liquid. [9]