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The Framingham Risk Score is a sex-specific algorithm used to estimate the 10-year cardiovascular risk of an individual. The Framingham Risk Score was first developed based on data obtained from the Framingham Heart Study , to estimate the 10-year risk of developing coronary heart disease. [ 1 ]
The Omni One Cohort, founded in 1994, looked at the possible influence of race and heritage as heart risk factors, as well as the changing racial background of Framingham. The Generation Three Cohort, founded in 2002, was a third-generation study consisting of children of the Offspring Cohort and grandchildren of the Original Cohort participants.
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The main aim of screening is to identify risk factors early and adopt preventive measures to reduce morbidity and mortality. [ 1 ] [ 2 ] Early identification of risk factors can lead to timely interventions, such as lifestyle changes, medications, or surgical treatment.
The well-established indications for the use of the CAC score include stratification of global cardiovascular risk for asymptomatic patients: intermediate risk based on the Framingham risk score (class I); low risk based on a family history of early coronary artery disease (CAD) (class IIa); and low-risk patients with diabetes (class IIa). [2]
There are various risk assessment systems for determining the risk of coronary artery disease, with various emphasis on the different variables above. A notable example is Framingham Score, used in the Framingham Heart Study. It is mainly based on age, gender, diabetes, total cholesterol, HDL cholesterol, tobacco smoking, and systolic blood ...
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Based on the Framingham Risk Scores, there are different thresholds that indicate whether treatment should be initiated. Individuals with a score of 20% are considered to have a high cardiovascular risk, a score of 10–19% indicates an intermediate risk, and patients with a score less than 10% are at low risk.