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  2. Acute myelomonocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_myelomonocytic_leukemia

    AMML can be treated depending on the degree of disease, age of patient, and current patient's health status. Treatment consists of a multi-drug chemotherapy regimen. [11] Chemotherapy drugs often used to treat AML are cytarabine and an anthracycline drug. Chemotherapy is broken down into 2 phases:

  3. Venetoclax - Wikipedia

    en.wikipedia.org/wiki/Venetoclax

    Venetoclax is also indicated as part of a combination therapy for acute myeloid leukemia (AML). [7] For this purpose it is used with azacitidine, decitabine, or low-dose cytarabine for newly diagnosed adults who are age 75 years or older, or those with other health problems where intensive chemotherapy cannot be used.

  4. Acute myeloid leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_myeloid_leukemia

    Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. [1] Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. [1]

  5. Acute monocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_monocytic_leukemia

    Acute monocytic leukemia (AMoL, or AML-M5) [2] is a type of acute myeloid leukemia. In AML-M5 >80% of the leukemic cells are of monocytic lineage. [3] This cancer is characterized by a dominance of monocytes in the bone marrow. There is an overproduction of monocytes that the body does not need in the periphery.

  6. FLAG (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/FLAG_(chemotherapy)

    FLAG is a chemotherapy regimen used for relapsed and refractory acute myeloid leukemia (AML). [1] The acronym incorporates the three primary ingredients of the regimen: . Fludarabine: an antimetabolite that, while not active toward AML, increases formation of an active cytarabine metabolite, ara-CTP, in AML cells;

  7. 7+3 (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/7+3_(chemotherapy)

    "7+3" in the context of chemotherapy is an acronym for a chemotherapy regimen that is most often used today (as of 2014) as first-line induction therapy (to induce remission) in acute myelogenous leukemia, [1] [2] excluding the acute promyelocytic leukemia form, which is better treated with ATRA and/or arsenic trioxide and requires less chemotherapy (if requires it at all, which is not always ...

  8. Acute myeloblastic leukemia with maturation - Wikipedia

    en.wikipedia.org/wiki/Acute_myeloblastic...

    Less than 1% of acute myeloid leukemia patients have the t(6;9) mutation. The rare translocation causes the formation of fusion oncoprotein DEK-NUP214 (Huret, 2005). DEK functions as a transcriptional repressor by interfering with histone acetyl transferases, regulator for a number of stem cells, and activates gene expression in myeloid cells ...

  9. Dementia - Wikipedia

    en.wikipedia.org/wiki/Dementia

    Dementia affects 5% of the population older than 65 and 20–40% of those older than 85. [271] Rates are slightly higher in women than men at ages 65 and greater. [ 271 ] The disease trajectory is varied and the median time from diagnosis to death depends strongly on age at diagnosis, from 6.7 years for people diagnosed aged 60–69 to 1.9 ...

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