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Baroreflex activation is distinct from vagal stimulation. [8] [9] Electrical stimulation of the external surfaces of the carotid sinus activates baroreceptors believed to be in the adventitia of the artery. This stimulates an afferent limb which activates central nervous system pathways that in turn exert two different but synergistic autonomic ...
Arterial baroreceptors are located in the carotid sinus (at the bifurcation of common carotid artery into external and internal carotids) and in the aortic arch. [5] The baroreceptors can identify the changes in both the average blood pressure or the rate of change in pressure with each arterial pulse.
The carotid sinus baroreceptor can be oversensitive to manual stimulation from the pressure applied at the carotid sinus at the carotid bifurcation. It is a condition known as 'carotid sinus hypersensitivity' (CSH), 'carotid sinus syndrome' or 'carotid sinus syncope', in which manual stimulation causes large changes in heart rate and blood ...
Baroreceptors are present in the atria of the heart and vena cavae, but the most sensitive baroreceptors are in the carotid sinuses and aortic arch.While the carotid sinus baroreceptor axons travel within the glossopharyngeal nerve (CN IX), the aortic arch baroreceptor axons travel within the vagus nerve (CN X).
High pressure receptors or high pressure baroreceptors are the baroreceptors found within the aortic arch and carotid sinus. They are only sensitive to blood pressures above 60 mmHg . When these receptors are activated they elicit a depressor response; which decreases the heart rate and causes a general vasodilation .
The resultant lowering of blood pressure is sensed by carotid sinus baroreceptors, and stimulates the baroreflex to inhibit vagal activity and stimulate the sympathetic nervous system – this increases heart rate and contractility, induces vasoconstriction, and tends to restore blood pressure.
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An additional mechanism involves compression of the baroreceptors of the carotid arteries, confusing the body into thinking blood pressure has risen. Due to the baroreflex, this inhibits sympathetic vasomotor and cardiac stimulation and increases parasympathetic stimulation of the heart causing vasodilation and a lowered heart rate. [1]