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Clinical Therapeutics – The relationship of autism to gluten (2013) This review found one double-blind study, which did not find any benefit from the gluten-free diet, and concluded that "Currently, there is insufficient evidence to support instituting a gluten-free diet as a treatment for autism." [8] Journal of Child Neurology – Evidence ...
The opioid excess theory is a theory which postulates that autism is the result of a metabolic disorder in which opioid peptides produced through metabolism of gluten and casein pass through an abnormally permeable intestinal membrane and then proceed to exert an effect on neurotransmission through binding with opioid receptors. [1]
The implementing regulation also clarifies how consumers are to be informed of the difference between foods that are naturally free of gluten and products that are specially formulated for gluten-intolerant persons. [80] Recognition of gluten-free packaged foods is facilitated by the crossed-grain symbol, representing a crossed ear of wheat ...
A part of people with gluten-related neuropathy or ataxia appears not to be able to tolerate even the traces of gluten allowed in most foods labeled as "gluten-free". [49] Whereas celiac disease requires adherence to a strict lifelong gluten-free diet, it is not yet known whether NCGS is a permanent or a transient condition.
The authors analyzed the prospective trials conducted to date that studied the efficacy of the gluten- and casein-free diet in children with ASD (4 in total). All of them compared gluten- and casein-free diet versus normal diet with a control group (2 double-blind randomized controlled trials, 1 double-blind crossover trial, 1 single-blind trial).
The test may be performed in people with suspected gluten-related disorders in very specific occasions and under medical supervision, for example in people who had started a gluten-free diet without performing duodenal biopsy. [1] [2] [3] Gluten challenge is discouraged before the age of 5 years and during pubertal growth. [4]
Depression in GSE has several causes; in the more severe CD, depression can be the result of lower vitamin adsorption [10] and essential fatty acid adsorption (see section on autism). Depression and anger may also be the result of lower quality of life issues as a result of gluten-free diet. [87]
As a result of this speculation, he has promoted the use of a gluten-free, casein-free diet to ameliorate the symptoms of autism, a theory he developed along with Kalle Reichelt. In addition, he has claimed that a protein found in milk may play a role in the etiology of autism. [2] He is also the former president of the World Autism Organization.