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Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. [3] [4] Generally it is used together with dietary changes and a statin. [5] Alone, it is less preferred than a statin. [4] It is taken by mouth. [4]
With median follow-up of 6 years, simvastatin+ezetimibe was found to reduce the primary outcome of CV mortality, major CV event, or nonfatal stroke (34.7% vs. 32.7%; P=0.016; NNT 50 per 7 years or NNT 350 per 1 year ). There was no reduction in all-cause or CV mortality with simvastatin+ezetimibe, though there was a reduction in MI and stroke. [6]
[citation needed] Annual cost to the UK National Health Service (NHS) in 2018, for 5–40 mg rosuvastatin daily (of one person) was £24-40, compared to £10-20 for 20–80 mg simvastatin. [38] In 2013, it was the fourth-highest-selling drug in the United States, accounting for approximately $5.2 billion in sales. [39]
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Earlier this week, AstraZeneca's (AZN) widely used cholesterol-lowering drug Crestor was approved by the U.S. Food and Drug Administration for use in people with normal cholesterol to prevent ...
Managing cholesterol at the site of absorption is an increasingly popular strategy in the treatment of hypercholesterolemia [citation needed].Cholesterol absorption inhibitors are known to have a synergistic effect when combined a class of antihyperlipidemics called statins, to achieve an overall serum cholesterol target.
A 2023 systematic review and meta-analysis looked into 14 trials of tirzepatide on more than 11,000 people with type 2 diabetes. ... The drugs cost about the same and can cause very similar side ...
The Drugs.com website is owned and operated by the Drugsite Trust, a privately held Trust administered by two New Zealand pharmacists, Karen Ann and Phillip James Thornton. [2] Operated on the IBM Cloud, Drugs.com provides information on some 24,000 drugs, was visited by 50 million users per month in 2021, and has a download time of one second. [3]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261
Working to be "the most powerful patient advocate in America" - Forbes