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  2. Phenotypic screening - Wikipedia

    en.wikipedia.org/wiki/Phenotypic_screening

    Phenotypic screening is a type of screening used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell or an organism in a desired manner. [1]

  3. Classical pharmacology - Wikipedia

    en.wikipedia.org/wiki/Classical_pharmacology

    Forward (classical) and reverse pharmacology approaches in drug discovery. In the field of drug discovery, classical pharmacology, [1] also known as forward pharmacology, [2] [3] [4] or phenotypic drug discovery (PDD), [5] relies on phenotypic screening (screening in intact cells or whole organisms) of chemical libraries of synthetic small molecules, natural products or extracts to identify ...

  4. High-content screening - Wikipedia

    en.wikipedia.org/wiki/High-content_screening

    High-content screening (HCS), also known as high-content analysis (HCA) or cellomics, is a method that is used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell in a desired manner.

  5. Drug design - Wikipedia

    en.wikipedia.org/wiki/Drug_design

    Phenotypic drug discovery is a traditional drug discovery method, also known as forward pharmacology or classical pharmacology. It uses the process of phenotypic screening on collections of synthetic small molecules, natural products, or extracts within chemical libraries to pinpoint substances exhibiting beneficial therapeutic effects.

  6. Chemogenomics - Wikipedia

    en.wikipedia.org/wiki/Chemogenomics

    Chemogenomics Staubli robot retrieves assay plates from incubators. Chemogenomics, or chemical genomics, is the systematic screening of targeted chemical libraries of small molecules against individual drug target families (e.g., GPCRs, nuclear receptors, kinases, proteases, etc.) with the ultimate goal of identification of novel drugs and drug targets. [1]

  7. 8 Common Cardiovascular Diseases for Men & How to Prevent Them

    www.aol.com/8-common-cardiovascular-diseases-men...

    Statins and other cholesterol-lowering drugs. Calcium channel blockers. Long-acting nitrates. Endovascular surgery. Coronary artery bypass surgery. Coronary artery stents. Arrhythmia.

  8. Drug discovery - Wikipedia

    en.wikipedia.org/wiki/Drug_discovery

    Another method for drug discovery is de novo drug design, in which a prediction is made of the sorts of chemicals that might (e.g.) fit into an active site of the target enzyme. For example, virtual screening and computer-aided drug design are often used to identify new chemical moieties that may interact with a target protein.

  9. ‘12 Badass Women’ by Huffington Post

    testkitchen.huffingtonpost.com/badass-women/...

    The Huffington Post reached out to historians across the country to create a list of women who deserve more recognition for their accomplishments.