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The molecular disease concept put forward in the 1949 paper also became the basis for Linus Pauling's view of evolution. In the 1960s, by which time it had been shown that sickle cell trait confers resistance to malaria and so the gene had both positive and negative effects and demonstrated heterozygote advantage , Pauling suggested that ...
The Linus Pauling Institute still exists, but moved in 1996 from Palo Alto, California, to Corvallis, Oregon, where it is part of the Linus Pauling Science Center at Oregon State University. [ 181 ] [ 182 ] [ 183 ] The Valley Library Special Collections at Oregon State University contain the Ava Helen and Linus Pauling Papers, including ...
One of Pauling's examples is olivine, M 2 SiO 4, where M is a mixture of Mg 2+ at some sites and Fe 2+ at others. The structure contains distinct SiO 4 tetrahedra which do not share any oxygens (at corners, edges or faces) with each other. The lower-valence Mg 2+ and Fe 2+ cations are surrounded by polyhedra which do share oxygens.
Some of these structures were proposed during the 1950s before the structure of the double helix was solved, most famously by Linus Pauling. Non-helical or "side-by-side" models of DNA were proposed in the 1970s to address what appeared at the time to be problems with the topology of circular DNA chromosomes during replication (subsequently ...
Vitamin C and the Common Cold is a popular book by Linus Pauling, first published in 1970, on vitamin C, its interactions with common cold and the role of vitamin C megadosage in human health. [1] The book promoted the idea that taking large amounts of vitamin C could reduce the duration and severity of the common cold .
In the late 1960s, Linus Pauling introduced the expression "orthomolecular" [11] to express the idea of the right molecules in the right amounts. [11] Since the first claims of medical breakthroughs with vitamin C by Pauling and others, findings on the health effects of vitamin C have been controversial and contradictory.
[68] [69] Linus Pauling advocated for the use of vitamin C to prevent and treat various diseases, especially the common cold and cancer. [70] [71] [72] Still, the arguments given in these books were not based on solid peer-reviewed medical research. Pauling published several books and articles on the topic, such as Vitamin C and the Common Cold ...
In 1951, Pauling published the structure of the alpha helix, a fundamentally important structural component of proteins. In early 1953, Pauling published a triple helix model of DNA, which subsequently turned out to be incorrect. [3] Both Crick, and particularly Watson, thought that they were racing against Pauling to discover the structure of DNA.
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