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PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: vitiligo, eczema, psoriasis, graft-versus-host disease, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen.
Basal-cell carcinomas are most commonly present on sun-exposed areas of the skin, especially the face. They rarely metastasize and rarely cause death. They are easily treated with surgery or radiation. Squamous-cell skin cancers are also common, but much less common than basal-cell cancers. They metastasize more frequently than BCCs.
On the positive side, UV exposure enables the synthesis of vitamin D 3, which is essential for bone health [1] and potentially plays a role in inhibiting certain cancers. [ 2 ] [ 3 ] While vitamin D can also be obtained through dietary supplements, [ 4 ] UV exposure offers benefits such as enhanced subdermal nitric oxide production and improved ...
Blood irradiation therapy is an alternative medical procedure in which the blood is exposed to low-level light (often laser light) for therapeutic reasons. [1] The practice was originally developed in the United States, [1] but most recent research on it has been conducted in Germany (by UV lamps) and in Russia (in all variants).
Mayo Clinic is a nonprofit hospital system with campuses in Rochester, Minnesota; Scottsdale and Phoenix, Arizona; and Jacksonville, Florida. [22] [23] Mayo Clinic employs 76,000 people, including more than 7,300 physicians and clinical residents and over 66,000 allied health staff, as of 2022. [5]
To prevent this the cell undergoes a morphological change into keratinocytes. These keratinocytes exhibit the capacity to release TNF-α (tumor necrosis factor - alpha) [5] that stop the growth of the tumor by promoting the death of the cell. If keratinocyte cells have been damaged by UVB radiation, the term "sunburn cell" or "SBC formation" is ...
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