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Simply switching the patient from 40 mg of morphine to 10 mg of levorphanol would be dangerous due to dose accumulation, and hence frequency of administration should also be taken into account. There are other concerns about equianalgesic charts. Many charts derive their data from studies conducted on opioid-naive patients.
Firocoxib, sold under the brand names Equioxx and Previcox among others, is a nonsteroidal anti-inflammatory drug of the COX-2 inhibitor (coxib) class, approved for use in horses (Equioxx) and for use in dogs (Previcox). [2] [4] [9] Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses. [10]
Eperisone hydrochloride is available as the brand name preparations Myonal and Epry as 50 mg sugar-coated tablets, or as 10% granules for oral administration. [6] An experimental form of the drug, as a transdermal patch system, has shown promising results in laboratory tests on rodents; however, this product is not currently available for human use.
Vaccination of dogs is the practice of animal vaccination applied to dogs. Programs in this field have contributed both to the health of dogs and to the public health . In countries where routine rabies vaccination of dogs is practiced, for example, rabies in humans is reduced to a very rare event.
In clinical pharmacology, dose refers to the amount of drug administered to a person, and dosage is a fuller description that includes not only the dose (e.g., "500 mg") but also the frequency and duration of the treatment (e.g., "twice a day for one week").
The total dose can be above the threshold for a deterministic effect, but if the dose is spread out over a long period of time, the effect is not observed. Consider the sunburn, a deterministic effect: [ 4 ] when exposed to bright sunlight for only ten minutes [ 5 ] at a high UV Index, that is to say a high average dose rate, [ 6 ] the skin can ...
Therefore, a drug given by the intravenous route will have an absolute bioavailability of 100% (f = 1), whereas drugs given by other routes usually have an absolute bioavailability of less than one. If we compare the two different dosage forms having same active ingredients and compare the two drug bioavailability is called comparative ...
Ripasudil (trade name Glanatec), a derivative of fasudil, is a rho kinase inhibitor drug ... Dogs Once a day in right eye and orally 13 weeks 2.0% in eye, 7.5 mg/kg ...
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