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  2. List of reagent testing color charts - Wikipedia

    en.wikipedia.org/wiki/List_of_reagent_testing...

    Reagent test Alcohols: Forms Lucas test in alcohols is a test to differentiate between primary, secondary, and tertiary alcohols. Alkaloids: Forms Froehde Liebermann Mandelin Marquis Mayer's Mecke Simon's: Amines, and amino acids: Forms Folin's: Barbiturates: Class Dille–Koppanyi Zwikker: Benzodiazepines: Class Zimmermann: Phytocannabinoids ...

  3. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    The substances are taken in the order of LSD, Mushrooms, MDMA, then ketamine. Each substance should be taken at the peak of the previous substance to maximize the synergistic effects. Ketamine can be re-dosed as needed to extend the trip. The result is a highly visual and euphoric experience with periods of deep dissociation. LSD: Mescaline ...

  4. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    Benzodiazepines can cause death when mixed with other CNS depressants such as opioids, alcohol, or barbiturates. [7] [8] [9] GHB combined with alcohol can lead to a long-lasting coma-like state (‘G-sleep’) or even accidental death, particularly in light of GHB's narrow threshold for overdose. Depressants combined with stimulants. For example:

  5. Marquis reagent - Wikipedia

    en.wikipedia.org/wiki/Marquis_reagent

    The above photo shows the positive results of the number 2 Marquis reagent presumptive drug test when used with a sample of opium. It is the primary presumptive test used in Ecstasy reagent testing kits. It can also be used to test for such substances as opiates (e.g. codeine, heroin), and phenethylamines (e.g. 2C-B, mescaline).

  6. Benzodiazepine overdose - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_overdose

    Benzodiazepines are one of the most highly prescribed classes of drugs, [7] and they are commonly used in self-poisoning. [8] [9] Over 10 years in the United Kingdom, 1512 fatal poisonings have been attributed to benzodiazepines with or without alcohol. [10] Temazepam was shown to be more toxic than the majority of benzodiazepines.

  7. Cross-tolerance - Wikipedia

    en.wikipedia.org/wiki/Cross-tolerance

    Benzodiazepine binding increases the binding of GABA and barbiturates maximize the time the pore is open. Both of these mechanisms allow for influx of chloride ions. When these drugs are taken together, especially with ethanol (drinking alcohol), there is a disproportionate increase in toxicity because the effects of both occur simultaneously ...

  8. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Polydrug use involving benzodiazepines and alcohol can result in an increased risk of blackouts, risk-taking behaviours, seizures, and overdose. [221] Dependence and tolerance, often coupled with dosage escalation, to benzodiazepines can develop rapidly among people who misuse drugs; withdrawal syndrome may appear after as little as three weeks ...

  9. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol. [ 9 ] [ 10 ] A 2005 medical review advised patients to avoid all citrus juices until further research clarifies the risks. [ 11 ]