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A photoreceptor cell is a specialized type of neuroepithelial cell found in the retina that is capable of visual phototransduction. The great biological importance of photoreceptors is that they convert light (visible electromagnetic radiation ) into signals that can stimulate biological processes.
Photoreceptor proteins typically consist of a protein attached to a non-protein chromophore (sometimes referred as photopigment, even so photopigment may also refer to the photoreceptor as a whole). The chromophore reacts to light via photoisomerization or photoreduction , thus initiating a change of the receptor protein which triggers a signal ...
The LGN is integral in the early steps of color processing, where opponent channels are created that compare signals between the different Photoreceptor cell types. The output of P-cells comprises red-green opponent signals. The output of M-cells does not include much color opponency, rather a sum of the red-green signal that evokes luminance ...
The stacked-disc structure of the detector portion of the cell allows for very high efficiency. Rods are much more common than cones, with about 120 million rod cells compared to 6 to 7 million cone cells. [2] Like cones, rod cells have a synaptic terminal, an inner segment, and an outer segment.
The photoreceptor cell-specific nuclear receptor (PNR), also known as NR2E3 (nuclear receptor subfamily 2, group E, member 3), is a protein that in humans is encoded by the NR2E3 gene. [5] PNR is a member of the nuclear receptor super family of intracellular transcription factors .
The R8 photoreceptor contains an activator of the RTK (receptor tyrosine kinase) for on a precursor R7 cell, called the bride of sevenless (BOSS). The binding of BOSS to sevenless stimulates a complex series of reactions involving the RTK (sevenless), MAP kinases, Ras and many more molecules to differentiate that precursor R7 photo receptor to ...
The pigments in photoreceptor proteins either change their conformation or undergo photoreduction when they absorb a photon. [3] This change in the conformation or redox state of the chromophore then affects the protein conformation or activity and triggers a signal transduction cascade. [3] Examples of photoreceptor pigments include: [4]
Information is conveyed from photoreceptor cells to bipolar cells via the release of the neurotransmitter glutamate at the ribbon synapse. [24] Conventional neurons encode information by changes in the rate of action potentials, but for complex senses like vision, this is not sufficient. Ribbon synapses enable neurons to transmit light signals ...