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The following is a table of drugs organized by their year of discovery. Naturally occurring chemicals in plants, including alkaloids, have been used since pre-history.In the modern era, plant-based drugs have been isolated, purified and synthesised anew.
In Europe, an estimated 37% of regular club-goers aged 14 to 35 used MDMA in the past year according to the 2015 European Drug report. [8] The highest one-year prevalence of MDMA use in Germany in 2012 was 1.7% among people aged 25 to 29 compared with a population average of 0.4%. [ 8 ]
The practice of reusing medical devices labeled for only one use began in hospitals in the late 1970s. [8] After a thorough review by the U.S. FDA in 1999 and 2000, [8] the agency released a guidance document for reprocessed SUDs that began regulating the sale of these reprocessed devices on the market, [9] under the condition that third-party reprocessors would be treated as the manufacturer ...
The history of Europe is traditionally divided into four time periods: prehistoric Europe (prior to about 800 BC), classical antiquity (800 BC to AD 500), the Middle Ages (AD 500–1500), and the modern era (since AD 1500). The first early European modern humans appear in the fossil record about 48,000 years ago, during the Paleolithic era.
These timelines of world history detail recorded events since the creation of writing roughly 5000 years ago to the present day. For events from c. 3200 BC – c. 500 see: Timeline of ancient history; For events from c. 500 – c. 1499, see: Timeline of post-classical history; For events from c. 1500, see: Timelines of modern history
Timeline of Serbian history; Timeline of Singaporean history; Timeline of Slovenian history; Timeline of South Africa; Timeline of Spanish history; Timeline of Sri Lankan history; Timeline of Sudanese history; Timeline of Swedish history; Timeline of Swiss history; Timeline of Syrian history
The timeline begins at the Bronze Age, as it is difficult to give even estimates for the timing of events prior to this, such as of the discovery of counting, natural numbers and arithmetic. To avoid overlap with timeline of historic inventions , the timeline does not list examples of documentation for manufactured substances and devices unless ...
1826 – Scottish explorer Alexander Gordon Laing becomes the first European to reach the fabled city of Timbuktu, but is murdered upon leaving the city. [99] 1827 – Jedediah Smith crosses the Sierra Nevada (via Ebbetts Pass) and the Great Basin. [29] 1828 – French explorer René Caillié is the first European to return alive from Timbuktu.