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Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic ; if symptoms appear, they typically begin 3 to 14 days after infection.
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Dengue fever: 172 [258] 2008 Zimbabwean cholera outbreak: 2008–2009 Zimbabwe: Cholera: 4,293 [259] 2009 Bolivian dengue fever epidemic: 2009 Bolivia: Dengue fever: 18 [260] 2009 Gujarat hepatitis outbreak: 2009 India Hepatitis B: 49 [261] Queensland 2009 dengue outbreak 2009 Queensland, Australia Dengue fever: 1+ (503 cases) [262]
The mosquito-borne virus has a long history in warm climates but is now also emerging in regions where it had been generally unheard of—such as in Europe and parts of the U.S.
fever, anemia, enlarged liver, enlarged spleen, death Leprosy † (Hansen's disease) 1975 Mycobacterium leprae and M. lepromatosis mycobacteria extensive contact (probably airborne disease) throughout the tropics 209,000 (2018) few skin lesions, [12] numbness: permanent damage to the skin, nerves, limbs, and eyes Dengue fever: 1999 dengue virus
Dengue fever is caused by infection through viruses of the family Flaviviridae. The illness is most commonly transmitted by Aedes aegypti mosquitoes in tropical and subtropical regions. [58] Dengue virus has four different serotypes, each of which are antigenically related but have limited cross-immunity to reinfection. [59]
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
Flavivirus, renamed Orthoflavivirus in 2023, [3] is a genus of positive-strand RNA viruses in the family Flaviviridae.The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, [4] as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek ...