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Steroid-induced skin atrophy is thinning of the skin as a result of prolonged exposure to topical steroids. In people with psoriasis using topical steroids it occurs in up to 5% of people after a year of use. [5] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8]
A narrow, high-pressure stream of liquid is made to penetrate the outermost layer of the skin (stratum corneum) to deliver medication to targeted underlying tissues of the epidermis or dermis ("cutaneous" injection, also known as classical "intradermal" injection), fat ("subcutaneous" injection), or muscle ("intramuscular" injection).
In medicine, a subcutaneous implant is an implant that is delivered under the skin into the subcutaneous tissue by surgery or injection and is used to deliver a drug for a long period of time. [1] [2] Examples of drugs that can be administered in this way include leuprorelin and the sex steroids estradiol [3] and testosterone. [citation needed]
Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion. A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis. The instruments are usually a hypodermic needle and a syringe.
The pharmacokinetics of nandrolone decanoate via subcutaneous injection closely resemble those of intramuscular injection. [45] However, subcutaneous injection is considered to be easier, more convenient, and less painful compared to intramuscular injection. [45] In addition, research suggests that most intramuscular injections in practice are ...
Injection into the subcutaneous tissue is a route of administration used for drugs such as insulin: because it possesses few blood vessels, the tissue absorbs drugs slowly. [10]: 135 Subcutaneous injection is believed to be the most effective manner to administer some drugs, such as human growth hormones. Just as the subcutaneous tissue can ...
Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
intra-articular or soft tissue, intralesional or intramuscular suspension 20, 40, 80 mg/ml Polyethylene glycol 3350, Polysorbate 80, Monobasic sodium phosphate, Dibasic sodium phosphate USP, Benzyl alcohol 2 added as a preservative methylprednisolone acetate 3: Depo-Medrol Parenteral: intra-articular or soft tissue, intralesional or intramuscular