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Acute kidney injury is diagnosed on the basis of clinical history and laboratory data. A diagnosis is made when there is a rapid reduction in kidney function, as measured by serum creatinine, or based on a rapid reduction in urine output, termed oliguria (less than 0.5 mL/kg/h for at least 6 hours). [21]
[7] [29] [16] Despite the use of supportive care, an estimated 33–40% of patients will die or have end-stage renal disease (ESRD) with the first clinical manifestation of aHUS, [22] [23] and 65% of patients will die, require dialysis, or have permanent renal damage within the first year after diagnosis despite plasma exchange or plasma ...
Hemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine. [1] The condition is caused by excessive intravascular hemolysis, in which large numbers of red blood cells (RBCs) are destroyed, thereby releasing free hemoglobin into the plasma. [2]
In MIDD, these abnormal immunoglobulins, or fragments of them, are deposited along the basement membrane of the kidney. This deposition damages the kidney, leading to renal insufficiency. The damage to the kidney may also prevent protein re-absorption by the kidney; instead of being reabsorbed, the proteins enter the urine.
Kidney failure, also known as renal failure or end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. [2]
However, this improvement is not definitive as some 50% to 60% of people with Nephrotic syndrome die and/or develop chronic kidney failure 6 to 14 years after this remission. On the other hand, between 10% and 20% of people have continuous episodes of remissions and relapses without dying or jeopardizing their kidney. The main causes of death ...
Hypomagnesemic hypercalciuric nephrocalcinosis (magnesium-losing kidney)[248250] PCLN1: 3q27: AR: Nephrocalcinosis, renal failure, ocular/hearing defects, polyruria, polydipsia, recurrent urinary tract infections, recurrent renal colic, normotensive: Plasma: ↓Mg, ↑PTH; Urine: ↑Ca, ↑Mg Distal Tubule/Collecting Duct: Liddle's syndrome ...
Nephroptosis is rare and abnormal condition in which the kidney drops down (ptosis) into the pelvis when the patient stands up. It is more common in women than in men. It has been one of the most controversial conditions in terms of both its diagnosis and its treatments.