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  2. Two's complement - Wikipedia

    en.wikipedia.org/wiki/Two's_complement

    Two's complement is the most common method of representing signed (positive, negative, and zero) integers on computers, [1] and more generally, fixed point binary values. Two's complement uses the binary digit with the greatest value as the sign to indicate whether the binary number is positive or negative; when the most significant bit is 1 the number is signed as negative and when the most ...

  3. Signed number representations - Wikipedia

    en.wikipedia.org/wiki/Signed_number_representations

    Addition of a pair of two's-complement integers is the same as addition of a pair of unsigned numbers (except for detection of overflow, if that is done); the same is true for subtraction and even for N lowest significant bits of a product (value of multiplication). For instance, a two's-complement addition of 127 and −128 gives the same ...

  4. Method of complements - Wikipedia

    en.wikipedia.org/wiki/Method_of_complements

    And if not, the 1 is not added and the result is one less than the radix complement of the answer, or the diminished radix complement, which does not require an addition to obtain. This method is used by computers that use sign-and-magnitude to represent signed numbers.

  5. Overflow flag - Wikipedia

    en.wikipedia.org/wiki/Overflow_flag

    Overflow cannot occur when the sign of two addition operands are different (or the sign of two subtraction operands are the same). [1] When binary values are interpreted as unsigned numbers, the overflow flag is meaningless and normally ignored. One of the advantages of two's complement arithmetic is that the addition and subtraction operations ...

  6. Complement system - Wikipedia

    en.wikipedia.org/wiki/Complement_system

    The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. [1]

  7. Booth's multiplication algorithm - Wikipedia

    en.wikipedia.org/wiki/Booth's_multiplication...

    The representations of the multiplicand and product are not specified; typically, these are both also in two's complement representation, like the multiplier, but any number system that supports addition and subtraction will work as well. As stated here, the order of the steps is not determined.

  8. Lectin pathway - Wikipedia

    en.wikipedia.org/wiki/Lectin_pathway

    Structure of mannose in its α-D mannopyranose form. Mannan is a polymer of mannose.. The lectin pathway or MBL pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, [1] in that, after activation, it proceeds through the action of C4 and C2 to produce activated complement proteins further down the cascade.

  9. Complementarity (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Complementarity_(molecular...

    Purines are larger than pyrimidines. Both types of molecules complement each other and can only base pair with the opposing type of nucleobase. In nucleic acid, nucleobases are held together by hydrogen bonding, which only works efficiently between adenine and thymine and between guanine and cytosine. The base complement A = T shares two ...