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A cancer vaccine, or oncovaccine, is a vaccine that either treats existing cancer or prevents development of cancer. [1] Vaccines that treat existing cancer are known as therapeutic cancer vaccines or tumor antigen vaccines. Some of the vaccines are "autologous", being prepared from samples taken from the patient, and are specific to that patient.
Anti-cancer vaccines can be preventive or be used as therapeutic treatment. [2] All such vaccines incite adaptive immunity by enhancing cytotoxic T lymphocyte (CTL) recognition and activity against tumor-associated or tumor-specific antigens (TAA and TSAs). Vaccines have been developed that prevent infection by some carcinogenic viruses. [40]
The dendritic cell-based cancer vaccine is an innovation in therapeutic strategy for cancer patients. Dendritic cells (DCs) are antigen presenting cells for the induction of antigen specific T cell response. [1] DC-based immunotherapy is safe and can promote antitumor immune responses and prolonged survival of cancer patients. [2]
A Memorial Sloan Kettering phase 1 clinical trial revealed an immune response in some pancreatic cancer patients. Study co-author Dr. Vinod Balachandran talks about the impact on future cancer care.
Both smoking and second-hand exposure from other smokers can lead to lung cancer and eventually death. [54] Prevention of tobacco use is paramount to prevention of lung cancer. Individual, community, and statewide interventions can prevent or cease tobacco use. 90% of adults in the U.S. who have ever smoked did so prior to the age of 20.
New research from the American Cancer Society on Thursday estimates nearly half of adult cancer deaths in the U.S. could be prevented by making lifestyle changes. New research from the American ...
Nearly half of cancer deaths could be prevented with lifestyle changes, new research finds. An estimated 40% of all cancer cases and 44% of all cancer deaths in adults over 30 years old in the ...
Cancer vaccines can also divided into specific or universal cancer vaccine based on the types of cancer it is used for. Specific cancer vaccines are only used to treat a particular type of cancer while universal vaccine can be used to treat different types of cancer. [4]
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