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Minimal residual disease (MRD), also known as Molecular residual disease, is the name given to small numbers of cancer cells that remain in a person either during or after treatment when the patient is in remission (no symptoms or signs of disease). Sensitive molecular tests are either in development or available to test for MRD.
– What does ‘remission’ mean? According to Cancer Research UK, remission means that there is no sign of cancer in a person’s body. And if there are any cancer cells left there are too few ...
A remission may be considered a partial remission or a complete remission. Each disease, type of disorder , or clinical trial can have its own definition of a partial remission. For example, a partial remission for cancer may be defined as a 50% or greater reduction in the measurable parameters of tumor growth as may be found on physical ...
In leukemia, a type of blood cancer, the ability of your bone marrow to produce normal blood cells is compromised. Rapidly developing, abnormal white blood cells crowd out healthy white blood ...
While remission doesn’t necessarily mean that cancer has been eradicated, it represents an important and positive step forward in the recovery journey. “Remission means, after you’ve been ...
Disseminating cancer cells can proliferate or become dormant depending on the microenvironment and factors such as the ERK/p38 ratio. Dormancy is a stage in cancer progression where the cells cease dividing but survive in a quiescent state while waiting for appropriate environmental conditions to begin proliferation again. [1]
Patients in response categories 4-9 should be considered as failing to respond to treatment (disease progression). Thus, an incorrect treatment schedule or drug administration does not result in exclusion from the analysis of the response rate. Precise definitions for categories 4-9 will be protocol specific.
Image source: Getty Images. 1. Missing the deadline. It might sound simple -- you need to take each year's required distribution before the deadline -- but these things have a way of becoming more ...