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In 2012, metoclopramide was one of the top 100 most prescribed medications in the United States. [8] It is available as a generic medication. [5] It is on the World Health Organization's List of Essential Medicines. [9] In 2022, it was the 245th most commonly prescribed medication in the United States, with more than 1 million prescriptions ...
Anticholinergic drugs are used to treat a variety of conditions: Dizziness (including vertigo and motion sickness-related symptoms) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications; Gastrointestinal disorders (e.g., peptic ulcers, diarrhea, pyloro spasm, diverticulitis, ulcerative colitis, nausea, and vomiting)
However, they can also cause constipation, dry mouth, and fatigue. Dolasetron (Anzemet) can be administered in tablet form or in an injection. Granisetron (Kytril, Sancuso) can be administered in tablet (Kytril), oral solution (Kytril), injection (Kytril), or in a single transdermal patch to the upper arm (SANCUSO).
There are many adverse effects, interactions and contraindications for antinicotinic and antimuscarinic agents. Adverse effects include hypotension, dry mouth, dry eyes etc. They interact with grapefruit juice and various medications, e.g. warfarin, metoclopramide. Therefore, cautions should be exercised and advice from medical professionals ...
Other dopamine antagonists and antiemetics can cause tardive dyskinesia, such as metoclopramide and promethazine, used to treat gastrointestinal disorders. Atypical antipsychotics are considered lower-risk for causing TD than their typical counterparts, with incidence rates of 13.1% and 32.4% respectively in short-term trials primarily ...
A link between these types of drugs and cognitive impairment isn't a totally new discovery, but for the first time, researchers used brain imaging techniques to determine the physical changes ...
A number of other drugs, such as antipsychotics and the tricyclic family of antidepressants, have incidental muscarinic antagonist activity which can cause unwanted side effects such as difficulty urinating, dry mouth and skin, and constipation.
These medications, such as levodopa, can also cause nausea as a side effect. Furthermore, anti-nausea drugs , such as metoclopramide , which do cross the blood–brain barrier , may worsen the extrapyramidal symptoms of Parkinson's disease.
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related to: can metoclopramide cause dry mouth list of medicines drugs