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Landau–Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, [1] or aphasia with convulsive disorder, is a rare neurological syndrome that develops during childhood. [2] It is named after William Landau and Frank Kleffner, who characterized it in 1957 with a diagnosis of six children. [3] [4]
Aphasia, also known as dysphasia, [a] is an impairment in a person’s ability to comprehend or formulate language because of damage to specific brain regions. [2] The major causes are stroke and head trauma; prevalence is hard to determine, but aphasia due to stroke is estimated to be 0.1–0.4% in developed countries. [3]
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Transcortical sensory aphasia is characterized as a fluent aphasia. Fluency is determined by direct qualitative observation of the patient’s speech to determine the length of spoken phrases, and is usually characterized by a normal or rapid rate; normal phrase length, rhythm, melody, and articulatory agility; and normal or paragrammatic speech. [5]
TMoA, or any other type of aphasia, is identified and diagnosed through the screening and assessment process. Screening can be conducted by an SLP or other professional when there is a suspected aphasia. [8] The screening does not diagnose aphasia, rather it points to the need for a further comprehensive assessment.
Mixed transcortical aphasia is characterized by severe speaking and comprehension impairment, but with preserved repetition. [6] People who suffer mixed transcortical aphasia struggle greatly to produce propositional language or to understand what is being said to them, yet they can repeat long, complex utterances or finish a song once they hear the first part.
Anomic aphasia (word retrieval failures) Phonemic paraphasia (sound errors in speech e.g. 'gat' for 'cat') Agrammatism (using the wrong tense or word order) As the disease develops, speech quantity decreases and many patients become mute. Cognitive domains other than language are rarely affected early on.
A rare update. Demi Moore revealed how ex-husband Bruce Willis’ aphasia has “progressed” since going public with the news in March 2022. Inside Demi Moore and Bruce Willis' Amicable Post ...