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  2. Acrolein - Wikipedia

    en.wikipedia.org/wiki/Acrolein

    Acrolein is toxic and is a strong irritant for the skin, eyes, and nasal passages. [5] The main metabolic pathway for acrolein is the alkylation of glutathione. The WHO suggests a "tolerable oral acrolein intake" of 7.5 μg per day per kg of body weight.

  3. Ferroptosis - Wikipedia

    en.wikipedia.org/wiki/Ferroptosis

    Since oxytosis/ferroptosis is a form of regulated cell death, [6] some of the molecules that regulate oxytosis/ferroptosis are involved in metabolic pathways that regulate cysteine exploitation, glutathione state, nicotinamide adenine dinucleotide phosphate (NADP) function, lipid peroxidation, and iron homeostasis.

  4. Glutathione - Wikipedia

    en.wikipedia.org/wiki/Glutathione

    Glutathione (GSH, / ˌ ɡ l uː t ə ˈ θ aɪ oʊ n /) is an organic compound with the chemical formula HOCOCH(NH 2)CH 2 CH 2 CONHCH(CH 2 SH)CONHCH 2 COOH. It is an antioxidant in plants , animals , fungi , and some bacteria and archaea .

  5. Allyl alcohol - Wikipedia

    en.wikipedia.org/wiki/Allyl_alcohol

    In rats, in vivo, allyl alcohol is metabolized by liver alcohol dehydrogenase to acrolein, which can cause damage to the microtubules of rat hepatocyte mitochondria and depletion of glutathione. [8] It is significantly more toxic than related alcohols. [5] [11] Its threshold limit value (TLV) is 2 ppm. It is a lachrymator. [5]

  6. Inverse electron-demand Diels–Alder reaction - Wikipedia

    en.wikipedia.org/wiki/Inverse_electron-demand...

    The orbitals with the largest coefficients in the reactive FMO's will overlap most strongly, and bond. Qualitatively, the largest FMO coefficients of the diene and dienophile are on gamma-carbon of acrolein and the terminal CH 2 of the methyl vinyl ether, respectively.

  7. Reactive aldehyde species - Wikipedia

    en.wikipedia.org/wiki/Reactive_aldehyde_species

    The two most commonly reported disease-associated pro-inflammatory RASP are malondialdehyde and 4-hydroxynonenal, [11] although many others, including acrolein, crotonaldehyde, acetaldehyde, and hexanal, have been described. [1] The toxicity of RASP include mutagenicity, aggregate formation, and generalized cytotoxicity. [1] [12]

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  9. Reuterin - Wikipedia

    en.wikipedia.org/wiki/Reuterin

    Besides, 3-hydroxypropionaldehyde suffers an spontaneous dehydration in aqueous solution, and the resulting molecule is called acrolein. [3] In fact, the term reuterin is the name given to the dynamic system formed by 3-hydroxypropionaldehyde, its hydrate, the dimer, and acrolein. This last molecule, acrolein, was recently included in reuterin ...

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