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The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...
In some countries, it is only available over-the-counter in packages containing seven or ten 10 mg doses. [47] [48] Cetirizine is available as a combination medication with pseudoephedrine, a decongestant. [49] The combination is often marketed using the same brand name as the cetirizine with a "-D" suffix (for example, Zyrtec-D). [50] [51]
Pseudoephedrine is widely available over-the-counter (OTC) in both single-drug and combination preparations. [30] [22] [13] [2] Availability of pseudoephedrine has been restricted starting in 2005 as it can be used to synthesize methamphetamine. [13] [2] Phenylephrine has replaced pseudoephedrine in many over-the-counter oral decongestant ...
Cetirizine/pseudoephedrine (Zyrtec-D) is an antihistamine and decongestant formulation. It is a fixed-dose combination drug containing 5 mg cetirizine hydrochloride and 120 mg pseudoephedrine hydrochloride for symptoms related to seasonal allergic rhinitis .
In addition to acting as an inverse agonist at the H 1 receptor, chlorphenamine has been found to act as a serotonin reuptake inhibitor (K d = 15.2 nM for the serotonin transporter). [13] [26] It has only weak affinity for the norepinephrine and dopamine transporters (K d = 1,440 nM and 1,060 nM, respectively). [13]
What you need to know about over-the-counter birth control OTC birth control pills are a newer option for people in the U.S. In July 2023, the Food and Drug Administration (FDA) approved Opill as ...
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