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The rate of Klinefelter syndrome among infertile males is 3.1%. The syndrome is the main cause of male hypogonadism. [68] One survey in the United Kingdom found that the majority of people with KS identify as male, however, a significant number have a different gender identity. [69] The prevalence of KS is higher than expected in transgender ...
48,XXYY syndrome is a condition related to the X and Y chromosomes (the sex chromosomes). People normally have 46 chromosomes in each cell.Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics.
Most XX males have a typical male-type phenotype at birth, so diagnosis tends to occur either at the onset of puberty, if traits such as gynaecomastia develop and are investigated, or later, when investigating infertility. [9] [24] Diagnosis at birth occurs more frequently in SRY-negative XX males, who are more likely to have ambiguous genitalia.
Dihydrotestosterone, also known as (DHT) will differentiate the remaining male characteristics of the external genitalia. [11] Further sex differentiation of the external genitalia occurs at puberty, when androgen levels again become disparate. Male levels of testosterone directly induce growth of the penis, and indirectly (via DHT) the prostate.
XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome. [1] There are usually few symptoms. [2] These may include being taller than average and an increased risk of learning disabilities.
Offspring have two sex chromosomes: an offspring with two X chromosomes (XX) will develop female characteristics, and an offspring with an X and a Y chromosome (XY) will develop male characteristics, except in various exceptions such as individuals with Swyer syndrome, that have XY chromosomes and a female phenotype, and de la Chapelle Syndrome ...
Sex differences in human physiology are distinctions of physiological characteristics associated with either male or female humans. These can be of several types, including direct and indirect, direct being the direct result of differences prescribed by the Y-chromosome (due to the SRY gene ), and indirect being characteristics influenced ...
[12] [13] Although variations exist and there may be a degree of overlap between typically male or female traits, [12] [13] the pelvis is the most dimorphic bone of the human skeleton and is therefore likely to be accurate when using it to ascertain a person's sex. [13] It differs both in overall shape and structure.