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Chloracne is particularly linked to toxic exposure to dioxins (byproducts of many chemical processes, including the manufacture of herbicides such as Agent Orange)—so much so that it is considered a clinical sign of dioxin exposure. The severity and onset of chloracne may follow a typical asymptotic dose-response relationship curve.
Agent Orange is a chemical herbicide and defoliant, one of the tactical use Rainbow Herbicides. It was used by the U.S. military as part of its herbicidal warfare program, Operation Ranch Hand, [1] during the Vietnam War from 1961 to 1971. [2] The U.S. was strongly influenced by the British who used Agent Orange during the Malayan Emergency.
TCDD is the most potent compound of its series (polychlorinated dibenzodioxins, known as PCDDs or simply dioxins) and became known as a contaminant in Agent Orange, an herbicide used in the Vietnam War. [4] TCDD was released into the environment in the Seveso disaster. [5] It is a persistent organic pollutant.
The defoliant Agent Orange contained trace amounts of dioxin impurities and caused severe health issues as a result. [70] The wood preservative pentachlorophenol often contained dioxins and dibenzofurans as impurities. [71] The Stockholm Convention banned the production and use of dioxins in 2001.
Agent Orange was the code name for one of the herbicides and defoliants the U.S. military used as part of its herbicidal warfare program, Operation Ranch Hand, during the Vietnam War from 1961 to 1971. It was a mixture of 2,4,5-T and 2,4-D.
The US-Vietnam Dialogue Group on Agent Orange/Dioxin, composed of members of the Aspen Institute, Vietnam National University, and Vietnam Veterans Association, is the most notable example of this civic response. Long-term programs and continued check-ups on the state of current plans to address Agent Orange are heavily monitored. [34]
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Agent Orange, a defoliant used by the British in the Malayan Emergency and the U.S. in the Vietnam War, was equal parts 2,4,5-T and 2,4-D (2,4-dichlorophenoxyacetic acid). 2,4,5-T itself is toxic with a NOAEL of 3 mg/kg/day and a LOAEL of 10 mg/kg/day. [3] Agent Pink contained 100% 2,4,5-T (dioxin