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Most 1-bromoalkanes are prepared by free-radical addition of hydrogen bromide to the 1-alkene. These conditions lead to anti-Markovnikov addition, giving the 1-bromo derivative. [2] 1-Bromohexane undergoes reactions expected of simple alkyl bromides. It can form Grignard reagents. [3]
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Medicine: Organic synthesis plays a vital role in drug discovery, allowing chemists to develop and optimize new drugs by modifying organic molecules. [9] Additionally, the synthesis of metal complexes for medical imaging and cancer treatments is a key application of chemical synthesis, enabling advanced diagnostic and therapeutic techniques. [10]
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The unimolecular nucleophilic substitution (S N 1) reaction is a substitution reaction in organic chemistry. The Hughes-Ingold symbol of the mechanism expresses two properties—"S N " stands for " nucleophilic substitution ", and the "1" says that the rate-determining step is unimolecular .
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