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  2. Prazosin - Wikipedia

    en.wikipedia.org/wiki/Prazosin

    Prazosin is active after taken by mouth and has a minimal effect on cardiac function due to its α 1-adrenergic receptor selectivity.When prazosin is started, however, heart rate and contractility can increase in order to maintain the pre-treatment blood pressures because the body has reached homeostasis at its abnormally high blood pressure.

  3. Management of post-traumatic stress disorder - Wikipedia

    en.wikipedia.org/wiki/Management_of_post...

    The advantage of using psychedelic drugs is that many of these drugs are not physically addictive, unlike drugs like nicotine. The disadvantages of using psychedelics include the risk of a "bad trip" causing the patient to feel unsafe and causing long-term negative impact on their mental state.

  4. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    The risk of first dose phenomenon may be reduced or eliminated by gradual-dose titration, since the adverse effects of Prazosin are dose-related. [7] This is also the case for Tamsulosin and it may be assumed that the others alpha-1 blockers work in a similar manner, since Tamsulosin is an alpha-1-a blocker and Prazosin is an alpha-1 blocker ...

  5. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  6. Treatments for PTSD - Wikipedia

    en.wikipedia.org/wiki/Treatments_for_PTSD

    Evidence-based, trauma-focused psychotherapy is the first-line treatment for PTSD. [8] [9] [6] Psychotherapy is defined as a treatment where a therapist and patient build a therapeutic relationship and focus on the patient's thoughts, attitudes, affect, behavior, and social development to lessen the patient's psychopathologies and functional impairment.

  7. First-dose phenomenon - Wikipedia

    en.wikipedia.org/wiki/First-dose_phenomenon

    Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-limiting and in most cases does not recur after the initial period of therapy or during subsequent dose titration. [3] The alpha blocker prazosin (Minipress) is most notorious for producing a first dose phenomenon.

  8. FDA issues a new warning about pain supplements linked to ...

    www.aol.com/news/fda-issues-warning-pain...

    The substance can cause side effects in the nervous system, heart and stomach, with some effects mimicking opioid toxicity and withdrawal, according to the Centers for Disease Control and Prevention.

  9. Adrenergic neuron blockers - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_neuron_blockers

    Each agent has its own off-label uses, some examples include Tamsulosin for urinary disorders, Prazosin for post-traumatic stress disorder-related nightmares and Raynaud phenomenon, Phentolamine for hypertensive crisis and extravasation of vasopressors, and Phenoxybenzamine for neurogenic bladder and prostate obstruction. [1]

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