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  2. ADME - Wikipedia

    en.wikipedia.org/wiki/ADME

    ADME is the four-letter abbreviation (acronym) for absorption, distribution, metabolism, and excretion, and is mainly used in fields such as pharmacokinetics and pharmacology. The four letter stands for descriptors quantifying how a given drug interacts within body over time.

  3. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    A drug's characteristics make a clear distinction between tissues with high and low blood flow. Enzymatic saturation: When the dose of a drug whose elimination depends on biotransformation is increased above a certain threshold the enzymes responsible for its metabolism become saturated. The drug's plasma concentration will then increase ...

  4. Category:Drug templates by ATC - Wikipedia

    en.wikipedia.org/wiki/Category:Drug_templates_by_ATC

    If the template has a separate documentation page (usually called "Template:template name/doc"), add [[Category:Drug templates by ATC]] to the <includeonly> section at the bottom of that page. Otherwise, add <noinclude>[[Category:Drug templates by ATC]]</noinclude>

  5. Drug metabolism - Wikipedia

    en.wikipedia.org/wiki/Drug_metabolism

    Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. More generally, xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as any drug ...

  6. Absorption (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Absorption_(pharmacology)

    Intravascular administration does not involve absorption, and there is no loss of drug. [4] The fastest route of absorption is inhalation. [5] Absorption is a primary focus in drug development and medicinal chemistry, since a drug must be absorbed before any medicinal effects can take place. Moreover, the drug's pharmacokinetic profile can be ...

  7. Biopharmaceutics Classification System - Wikipedia

    en.wikipedia.org/wiki/Biopharmaceutics...

    According to the Biopharmaceutics Classification System (BCS) drug substances are classified to four classes upon their solubility and permeability: [1] Class I – high permeability, high solubility. Example: metoprolol, paracetamol [2] Those compounds are well absorbed and their absorption rate is usually higher than excretion.

  8. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    Drug administration via the nasal cavity yields rapid drug absorption and therapeutic effects. [33] This is because drug absorption through the nasal passages does not go through the gut before entering capillaries situated at tissue cells and then systemic circulation and such absorption route allows transport of drugs into the central nervous ...

  9. Liberation (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Liberation_(pharmacology)

    A limiting factor in the adsorption of pharmaceutical drugs is the degree to which they are ionized, as cell membranes are relatively impermeable to ionized molecules. The characteristics of a medication's excipient play a fundamental role in creating a suitable environment for the correct absorption of a drug.

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