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A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]
Endocrine disruptors are exogenous substances that act like hormones in the endocrine system and disrupt the physiologic function of endogenous hormones. They are sometimes also referred to as hormonally active agents , endocrine disrupting chemicals , or endocrine disrupting compounds .
The name given to these exogenous (coming from an external source) hormones is endocrine disruptors, due to their tendency to mimic the behaviors of naturally produced bodily hormones. [15] Endocrine disruptors have also been found to affect the levels and behaviors of a number of other bodily hormones.
Xenoestrogens are a type of xenohormone that imitates estrogen.They can be either synthetic or natural chemical compounds.Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any ...
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Endocrine disruptors are molecules that alter the structure or function of the endocrine system. These chemicals can act as a part of developmental toxicity because they can alter hormonal pathways in the endocrine system, leading to negative health effects. One of the most common endocrine disruptor is Bisphenol A (BPA).
BPA is an example of an endocrine disruptor which negatively affects reproductive development by acting as an estrogen mimicker (xenoestrogen) and a likely androgen mimicker. [46] Bisphenol A exposure in fetal female rats leads to mammary gland morphogenesis , increased formation of ovarian tumors , and increased risk of developing mammary ...
It is a rare endocrine disease caused by low levels of parathyroid hormone that impact multiple organs and affects an estimated 70,000 to 90,000 people in the United States, according to the company.