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Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
In a clinical trial of dogs with atopic dermatitis, treatment success for pruritus occurred in a significantly greater percentage of the dogs treated with APOQUEL (66 percent) vs. (4 percent) of ...
The condition of a dog's skin and coat is also an important indicator of its general health. Skin disorders of dogs vary from acute, self-limiting problems to chronic or long-lasting problems requiring life-time treatment. Skin disorders may be primary or secondary (due to scratching, itch) in nature, making diagnosis complicated.
There are several aspects to treatment: breaking the "itch-scratch" cycle by clipping the fur and cleaning the skin; [5] addressing the underlying painful or itchy condition which initially caused the animal to begin scratching; [2] and relieving the dog's discomfort, for example with steroid medications. [3]
Fluocinonide is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. [3] It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort. [3] A common potential adverse effect is skin atrophy (thinning of the skin). [4]
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Antipruritics, abirritants, [1] or anti-itch drugs, are medications that inhibit itching (Latin: pruritus).Itching is often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, mites, and contact dermatitis and urticaria caused by plants such as poison ivy (urushiol-induced contact dermatitis ...
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