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Research suggests that 70 percent of people with bipolar disorder experience their first manic episode between 15 and 24 years old, though it can happen later in life. Severe bipolar episodes can ...
Patients with bipolar disorder often have a less stable and more variable circadian activity. [2] Circadian activity disruption can be apparent even if the person concerned is not currently ill. [3] [4] A decreased need for sleep is a symptom of both a manic episode and a hypomanic episode [5] in bipolar disorder.
Onset after adolescence is connected to better prognoses for both genders, and being male is a protective factor against higher levels of depression. For women, better social functioning before developing bipolar disorder and being a parent are protective towards suicide attempts. [173]
Bipolar I: People with bipolar I disorder have had at least one manic episode along with a period of major depression or less severe mania. People with bipolar I can also have an episode of ...
Excessive levels of lithium can be harmful to the kidneys, and increase the risk of side effects in general. As a result, kidney function and blood levels of lithium are monitored in patients being treated with lithium. [2] Therapeutic plasma levels of lithium range from 0.5 to 1.5 mEq/L, with levels of 0.8 or higher being desirable in acute ...
The cause of Bipolar disorder can be attributed to misfiring neurotransmitters that overstimulate the amygdala, which in turn causes the prefrontal cortex to stop working properly. The bipolar patient becomes overwhelmed with emotional stimulation with no way of understanding it, which can trigger mania and exacerbate the effects of depression.
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