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  2. Genetic drift - Wikipedia

    en.wikipedia.org/wiki/Genetic_drift

    Genetic drift, also known as random genetic drift, allelic drift or the Wright effect, [1] is the change in the frequency of an existing gene variant in a population due to random chance. [ 2 ] Genetic drift may cause gene variants to disappear completely and thereby reduce genetic variation . [ 3 ]

  3. Hardy–Weinberg principle - Wikipedia

    en.wikipedia.org/wiki/Hardy–Weinberg_principle

    Each line shows one of the three possible genotypes. In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.

  4. Genetic hitchhiking - Wikipedia

    en.wikipedia.org/wiki/Genetic_hitchhiking

    It also assumes that the behavior of neutral allele frequencies can be described by the mathematics of genetic drift. Genetic hitchhiking has therefore been viewed as a major challenge to neutral theory, and an explanation for why genome-wide versions of the McDonald–Kreitman test appear to indicate a high proportion of mutations becoming ...

  5. Population genetics - Wikipedia

    en.wikipedia.org/wiki/Population_genetics

    ISOGG. v. t. e. Population genetics is a subfield of genetics that deals with genetic differences within and among populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as adaptation, speciation, and population structure. [1]

  6. Coalescent theory - Wikipedia

    en.wikipedia.org/wiki/Coalescent_theory

    Coalescent theory can also be used to model the amount of variation in DNA sequences expected from genetic drift and mutation. This value is termed the mean heterozygosity, represented as ¯. Mean heterozygosity is calculated as the probability of a mutation occurring at a given generation divided by the probability of any "event" at that ...

  7. Fixation (population genetics) - Wikipedia

    en.wikipedia.org/wiki/Fixation_(population_genetics)

    Fixation (population genetics) In population genetics, fixation is the change in a gene pool from a situation where there exists at least two variants of a particular gene (allele) in a given population to a situation where only one of the alleles remains. That is, the allele becomes fixed. [1] In the absence of mutation or heterozygote ...

  8. Population size - Wikipedia

    en.wikipedia.org/wiki/Population_size

    Appearance. In population genetics and population ecology, population size (usually denoted N) is a countable quantity representing the number of individual organisms in a population. Population size is directly associated with amount of genetic drift, and is the underlying cause of effects like population bottlenecks and the founder effect. [ 1 ]

  9. Linkage disequilibrium - Wikipedia

    en.wikipedia.org/wiki/Linkage_disequilibrium

    Linkage disequilibrium. In population genetics, linkage disequilibrium (LD) is a measure of non-random association between segments of DNA (alleles) at different positions on the chromosome (loci) in a given population based on a comparison between the frequency at which two alleles are detected together at the same loci versus the frequencies ...