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Lung cancer is the most diagnosed and deadliest cancer worldwide, with 2.2 million cases in 2020 resulting in 1.8 million deaths. [3] Lung cancer is rare in those younger than 40; the average age at diagnosis is 70 years, and the average age at death 72. [2] Incidence and outcomes vary widely across the world, depending on patterns of tobacco use.
Lung cancer staging is the assessment of the extent to which a lung cancer has spread from its original source. As with most cancers, staging is an important determinant of treatment and prognosis. In general, more advanced stages of cancer are less amenable to treatment and have a worse prognosis.
Lung tumor; A chest X-ray showing a tumor in the lung (marked by arrow) Specialty: Oncology Pulmonology: Symptoms: Coughing (including coughing up blood), weight loss, shortness of breath, chest pains [1] Complications: Lung cancer: Causes: Smoking Radon gas Asbestos Air pollution Genetics
Small cell lung cancer is often treated as a systematic disease due to its tendency for early dissemination, [4] thus, instead of the traditional TNM staging system, the Veterans' Administration Lung Study Group (VALSG) introduced a simplified 2-stage system in the 1950s to divide small cell lung cancer into limited stage and extensive stage. [7]
Squamous-cell carcinoma of the lung is closely correlated with a history of tobacco smoking, more so than most other types of lung cancer.According to the Nurses' Health Study, the relative risk of SCC is approximately 5.5, both among those with a previous duration of smoking of 1 to 20 years, and those with 20 to 30 years, compared to never-smokers. [2]
The Tony-Award nominated actor's daughter Nicole Burley told The New York Times he died on Feb. 7, 2025, at his Manhattan home following complications with lung cancer.
Complications may include pulmonary hypertension, respiratory failure, pneumothorax, and lung cancer. [ 2 ] Causes include environmental pollution, certain medications, connective tissue diseases , infections, and interstitial lung diseases .
Radiation-induced lung injury (RILI) is a general term for damage to the lungs as a result of exposure to ionizing radiation. [1] In general terms, such damage is divided into early inflammatory damage ( radiation pneumonitis ) and later complications of chronic scarring ( radiation fibrosis ).