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Extraskeletal myxoid chondrosarcoma (EMC) is an ultra-rare mesenchymal neoplasm with uncertain differentiation, which arises mostly in the deep soft tissue of proximal extremities and limb girdles. EMC is marked by a translocation involving the NR4A3 gene, which can be fused in-frame with different partners, most often EWSR1 or TAF1 .
Introduction: Extraskeletal myxoid chondrosarcoma is a rare form of soft tissue sarcoma characterized by a unique chromosomal translocation involving the NR4A3 gene on chromosome 9. It is most frequently diagnosed in the proximal extremities of older adult males and is notable for its insidious growth with predilection for local recurrence and ...
Extraskeletal myxoid chondrosarcoma (EMC) is a rare low-grade malignant mesenchymal neoplasm of the soft tissues, that differs from other sarcomas by unique histology and characteristic chromosomal translocations.
Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant soft tissue sarcoma (STS) that accounts for less than 3% of all soft tissue tumors. The conventional treatment for primary EMC is wide local excision with or without radiation therapy.
Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue tumor characterized by uniform spindle cells arranged in a reticular growth pattern in abundant myxoid stoma. 1, 2 Considered to be slow growing, it generally arises in the deep soft tissues of the proximal limbs but several unusual sites such as the scrotum and finger have been ...
Extraskeletal myxoid chondrosarcoma (EMC) is a rare low-grade malignant mesenchymal neoplasm of uncertain differentiation characterized by abundant myxoid matrix located in the soft tissues. It affects mainly the soft tissues of the proximal end of long bones.
Extraskeletal myxoid chondrosarcoma (EMC) is a very rare sarcoma subtype, which usually arises in the extremities, although it can originate from any anatomic site, and despite the name suggesting a soft-tissue-only location, there are reports of primary ECM of the bone (1–3).
Extraskeletal myxoid chondrosarcoma (EMC) is an ultra-rare sarcoma subtype with an incidence of <1/1,000,000 inhabitants/year. It usually occurs in adults, with a median age of onset in the fifth decade and only a few cases have been reported in childhood and adolescence [ 1 , 2 ].
Extraskeletal myxoid chondrosarcoma (EMC) is a very rare type of soft tissue sarcoma, which is a type of cancer. It: is thought to occur when chromosomes in cells break and re-join in the wrong way. Researchers are still trying to find out why this happens and whether this causes EMC.
Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma that was recognized as a distinct pathologic entity by Stout and Verner in 1953 (1).