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Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
Structure of chlorhexidine, a bisbiguanide antiseptic.. Bisbiguanides are a class of chemically related compounds known for their bactericidal properties. Generally considered to be of the generic formula: R 1 R 2 N.C(:NR 6)NH.C(:NH)NH.CH 2 X--(CH 2) 3 NH.C(:NH)NH.C(:NR 7)NR 3 R 4 V. [1] These compounds include the antiseptics chlorhexidine and alexidine.
Polyhexanide (polyhexamethylene biguanide, PHMB) is an antimicrobial compound suitable for clinical use in critically colonized or infected acute and chronic wounds. The physicochemical action on the bacterial envelope prevents or impedes the development of resistant bacterial strains.
Chlorhexidine [1] is a disinfectant and antiseptic with the molecular formula C 22 H 30 Cl 2 N 10, which is used for skin disinfection before surgery and to disinfect surgical instruments. [2] It is also used for cleaning wounds , preventing dental plaque , treating yeast infections of the mouth , and to keep urinary catheters from blocking. [ 3 ]
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Biguanides reduce hepatic glucose output and increase uptake of glucose by the periphery, including skeletal muscle. Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs ...
Alcohols applied to the skin are used to disinfect skin before a needle stick and before surgery. [2] They may also be used as a hand sanitizer; [2] to clean other areas; [2] and in mouthwashes. [3] [4] [5] Taken by mouth or injected into a vein, ethanol is used to treat methanol or ethylene glycol toxicity when fomepizole is not available. [1]
A reducing end of a carbohydrate is a carbon atom that can be in equilibrium with the open-chain aldehyde or keto form . If the joining of monomers takes place at such a carbon atom, the free hydroxy group of the pyranose or furanose form is exchanged with an OH-side-chain of another sugar, yielding a full acetal. This prevents opening of the ...