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Lyme disease, also known as Lyme borreliosis, is a tick-borne disease caused by species of Borrelia bacteria, transmitted by blood-feeding ticks in the genus Ixodes. [4] [9] [10] The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. [1]
"Erythema migrans is the only manifestation of Lyme disease in the United States that is sufficiently distinctive to allow clinical diagnosis in the absence of laboratory confirmation." [8] [9] Often, but not always, mentions of a target lesion (bull's-eye lesion) are talking about erythema migrans. However, the appearance of erythema migrans ...
Symptom assessment is a key component of dry eye diagnosis – to the extent that many believe dry eye syndrome to be a symptom-based disease. Several questionnaires have been developed to determine a score that would allow for a diagnosis. The McMonnies & Ho dry eye questionnaire is often used in clinical studies of dry eyes. [29]
What it looks like: The most recognizable reaction on this list is the bullseye rash—a large, red, target-like rash that signals the early stages of Lyme disease from the bite of an infected ...
In dermatology, a target lesion or bull's-eye lesion, named for its resemblance to the bull's-eye of a shooting target, is a rash with central clearing. It occurs in several diseases, as follows: Target lesions are the typical lesions of erythema multiforme, in which a vesicle is surrounded by an often hemorrhagic maculopapule. Erythema ...
Lyme disease is also known to cause swelling around the nerves that control the facial muscles, essentially pinching the nerve and causing facial nerve palsy, where facial muscles become weak or even paralyzed, which can make it hard to smile or close the eye. With Lyme disease, this condition is often bilateral, meaning it happens on both ...
Eight are known to cause Lyme disease or Borreliosis. [6] The major Borrelia species causing Lyme disease are Borrelia burgdorferi, Borrelia afzelii, and Borrelia garinii. [23] All species that cause Lyme disease are referred to collectively as B. burgdorferi sensu lato, [10] while B. burgdorferi itself is specified as B. burgdorferi sensu stricto.
Diabetes, for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
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