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Iodine-131 (131 I, I-131) is an important radioisotope of iodine discovered by Glenn Seaborg and John Livingood in 1938 at the University of California, Berkeley. [3] It has a radioactive decay half-life of about eight days. It is associated with nuclear energy, medical diagnostic and treatment procedures, and natural gas production.
The test was first introduced in 1956, using iodine-131 diodrast. [25] [26] Later developments included iodine-131, and then iodine-123, labelled ortho-Iodohippuric acid (OIH, marketed as Hippuran). [27] [28] 99m Tc-MAG3 has replaced 131 I-OIH because of better quality imaging regardless of the level of kidney function, [29] and lower radiation ...
Iodine-124 can be made by numerous nuclear reactions via a cyclotron. The most common starting material used is 124 Te. Iodine-124 as the iodide salt can be used to directly image the thyroid using positron emission tomography (PET). [9] Iodine-124 can also be used as a PET radiotracer with a usefully longer half-life compared with fluorine-18 ...
The radioactive iodine uptake test is a type of scan used in the diagnosis of thyroid problems, particularly hyperthyroidism. It is entirely different from radioactive iodine therapy (RAI therapy), which uses much higher doses to destroy cancerous cells. The RAIU test is also used as a follow-up to RAI therapy to verify that no thyroid cells ...
Iodine is the fourth halogen, being a member of group 17 in the periodic table, below fluorine, chlorine, and bromine; since astatine and tennessine are radioactive, iodine is the heaviest stable halogen. Iodine has an electron configuration of [Kr]5s 2 4d 10 5p 5, with the seven electrons in the fifth and outermost shell being its valence ...
Iodine-123 (123 I) is a radioactive isotope of iodine used in nuclear medicine imaging, including single-photon emission computed tomography (SPECT) or SPECT/CT exams. The isotope's half-life is 13.2232 hours; [1] the decay by electron capture to tellurium-123 emits gamma radiation with a predominant energy of 159 keV (this is the gamma primarily used for imaging).
Unlike the Wolff–Chaikoff effect, the Plummer effect does not prevent the thyroid from taking up radioactive iodine, e.g. in the case of nuclear emergencies.Therefore, "plummering" with high-dose iodine is only effective in a short time window after the release of radionuclides. [9]
Iodine-129 (129 I) is a long-lived radioisotope of iodine that occurs naturally but is also of special interest in the monitoring and effects of man-made nuclear fission products, where it serves as both a tracer and a potential radiological contaminant.