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[1] By 2007, the ketogenic diet was available from around 75 centres in 45 countries, and less restrictive variants, such as the modified Atkins diet, were in use, particularly among older children and adults. The ketogenic diet was also under investigation for the treatment of a wide variety of disorders other than epilepsy. [1]
Variations on the ketogenic diet, including the Modified Atkins Diet, and diets based on MCT oil have also been shown to be beneficial for some GLUT1 deficiency patients. [18] While the classic ketogenic diet is commonly used for younger children, compliance with the ketogenic diet can be difficult for older children and adults.
The original ketogenic diet is a high-fat, low-carbohydrate diet developed in the 1920s and used to treat drug-resistant childhood epilepsy. [ 73 ] [ 74 ] Most epilepsy specialists order these children to eat 80% of the diet from fat by weight (90% of calories), plus carbohydrate-free vitamins and minerals to prevent vitamin deficiency . [ 75 ]
A ketogenic diet also improved the symptoms of an infant with PFK deficiency. The logic behind this treatment is that the low-carb high fat diet forces the body to use fatty acids as a primary energy source instead of glucose. This bypasses the enzymatic defect in glycolysis, lessening the impact of the mutated PFKM enzymes.
Ketogenic diet. The ketogenic or "keto" diet involves intake of less than 50 g of carbohydrates daily along with increased fat and protein amounts. [45] One type of ketogenic or low carbohydrate diet is the "Atkins" Diet, which does not restrict protein and fat amounts. [12] Other ketogenic diets restrict the total amount of daily proteins and ...
Ketogenesis pathway. The three ketone bodies (acetoacetate, acetone, and beta-hydroxy-butyrate) are marked within orange boxes. Ketogenesis is the biochemical process through which organisms produce ketone bodies by breaking down fatty acids and ketogenic amino acids.
The healthy kidney diet restricts large amounts of protein, which are hard for the kidney to break down, but especially limits potassium and phosphorus-rich foods and beverages. Liquid intake is often limited as well. [55] [57] Ketogenic diet: A high-fat, low-carb diet
Keto diet may refer to: A low-carbohydrate , high-fat diet mainly used for weight loss in adults Ketogenic diet , a special diet for treating epilepsy, mostly in children
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