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Studies indicate that 5-HT 2C receptor activation will regulate appetite and food consumption, most likely by promoting satiety through appetite suppression by activation of 5-HT 2C. Consequently, selective agents with high affinity for this receptor over 5-HT 2B and 5-HT2 2A are being developed for the treatment of obesity.
Amphetamine sulfate (also known as amfetamine) – US FDA-approved for the treatment of exogenous obesity under the brand name "Evekeo". [21] Methylphenidate; Cocaine [22] Caffeine [23] Glucomannan [24] [25] Leptin [26] Lisdexamphetamine - US FDA approved for the treatment of binge-eating disorder in adults under the brand name "Vyvanse". [27]
Approved for weight management (short-term) by the FDA but not the European Medicines Agency [54] 10% [55] or 8.25 kilograms (18.2 lb) [56] Naltrexone/bupropion: Contrave Approved for weight management (chronic) in the US and EU [57] 5 percent [17] Liraglutide: Saxenda GLP-1 receptor agonist: Approved for weight management (chronic) 4 percent ...
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use. The drug acts as a highly selective serotonin releasing agent ...
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Mazindol is used in short-term (i.e., a few weeks) treatment of obesity, in combination with a regimen of weight reduction based on caloric restriction, exercise, and behavior modification in people with a body mass index greater than 30, or in those with a body mass index greater than 27 in the presence of risk factors such as hypertension, diabetes, or hyperlipidemia.
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The British National Formulary (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service (NHS).
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